Sunday, September 8th 2019
16:00 – 19:00 Welcome of the meeting attendees
19:00 Welcome drink and Dinner
21:00 Plenary lecture
Anne Feltz (Institute of Biology of Ecole Normale Supérieure, Paris)
“30 years of ion channel history”
Monday, September 9th 2019
08:15 Opening session
08:30 Symposium 1: “Ionic channels and autism”
Organized by Jean-Louis Bossu (Institut des Neurosciences Cellulaires et Intégratives, Université de Strasbourg, France)
Diane Papazian (Los Angeles, USA): Altered gating in mutant Kv4.2 channel associated with autism and epilepsy
Igor Medina (Marseille, France) : Causal links between impaired developmental neuronal chloride homeostasis and formation of Autistic Spectrum Disorders
Enrico Cherubini (Roma, Italy) : Impairment of GABAergic signalling in Autism Spectrum Disorders
Selected speaker: Eric Hosy (Bordeaux, France): Nanoscale co-organization and co-activation of AMPAR, NMDAR and mGluR at the synapse
10:15 Coffee break
10:30 Oral communication session 1: "New insights in ion channels pharmacology"
Organized by Sylvie Diochot (IPMC, University of Nice-Sophia Antipolis, France)
Ines ELBini Dhouib (Tunis, Tunisia): Potential neuroprotective effect of bee venom on aluminum chloride-induced Alzheimer's disease on rats
Zhong Peng (Lausanne, Switzerland): Acid-sensing ion channels of the hypothalamus are regulated by hydrogen sulphide.
Léa Réthoré (Angers, France): BREVENAL PREVENTS CIGUATOXIN AND BREVETOXIN ACTIVATION OF NAV CHANNELS..
Osbaldo Lopez-Charcas (Tours, France): Biophysical characterization of new small-molecule blockers of nNaV1.5 channels expressed in breast cancer cells
11:30 1-minute oral presentation for posters
14:00 Poster session 1
15:30 Poster session 2
17:00 Symposium 2: “Ion channels and skin functions”
Organized by Aubin Penna (Laboratoire STIM, University of Poitier, France)
Hongzhen HU (St. Louis, USA): "Cutaneous ion channel mechanisms of itch signaling".
V'yacheslav LEHEN’KYI (Lille, France): TRP channels and Skin homeostasis.
Elena OANCEA (Providence, USA): "Intracellular ion channels that regulate skin pigmentation".
Selected speaker: Adélaïde Doray (Tours, France): The role of the auxiliary NaVβ4 subunit in maintaining epithelial phenotype
18:30 Annual meeting of the association « Canaux ioniques »
19:30 Apéritif Sétois
Tuesday, September 10th 2019
08:30 Symposium 3: Glutamate ligand-gated channels
Organized by Laurent Fagni (IGF, University of Montpellier, France)
Pierre Paoletti (Paris, France): New types of NMDA receptors
Christophe Mulle (Bordeaux, France): Kainate receptors in temporal lobe epilepsy: a translational journey
Ludovic Tricoire (Paris, France): The delta family of glutamate receptors: role in excitatory synaptic transmission
Selected speaker: Perrine Inquimbert (Strasbourg, France): Plasticity of inhibitory synaptic transmission under the control of NMDA receptors in the dorsal horn of the spinal cord
10:15 Coffee break
10:30 Symposium 4: Ion channels in cancer therapy resistance
Organized by Lise Rodat-Despoix (LPCM, University of Amiens, France)
Federica Wolf (Roma, Italy): Magnesium-Specific Ion Channels in Chemoresistance: Is There a Role for Magnesium?
Geert Bultynck (Leuven, Belgium): Ca2+-signaling modulation by anti-apoptotic Bcl-2 proteins: from molecular mechanisms towards translational avenues
Annarosa Arcangeli (Florence, Italy): Targeting potassium channels to overcome chemoresistance in gastrointestinal cancers
Selected speaker: Charlotte Dubois (Lille, France): Apoptosis mediated by Mitochondrial Ca2+ Overload Requires Inhibition of Autophagy Revealing a Widespread Vulnerability of Cancer Cells
14:00 Special social events for 30th anniversary of association « Canaux ioniques » : Boat excursion with Sète Croisières : One hour guided tour of the fishing port, commercial port and marina, followed by a sea excursion along the rocky 'corniche' with underwater viewing. (http://www.sete-croisieres.com/).
19:00 Poster Prize session
19:30 Apéritif and special dinner
22:00 Evening Party
Wednesday, September 11th 2019
09:30 Oral communication session 2
Organized by Dimitra Gkika (Laboratoire de Physiologie Cellulaire, University of Lille, France)
Olivier Bignucolo (Lausanne, Switzerland): BIOMOLECULAR MODELLING OF ACID-SENSING ION CHANNELS
Côme Camus (Bordeaux, France): PHOSPHORYLATION OF PSD95 AS POTENTIAL LINK BETWEEN SYNAPTIC AND STRUCTURAL PLASTICITIES
Mathilde Folacci (Grenoble, France): Design of light-modulated inward rectifying potassium channels
Kerstin K. Viet (Frankfurt am Main, Germany): Structure and Ca2+ interaction of the Extracytosolic/Lumenal Domain (ELD) of the human TRPML2 ion channel
10:30 Coffee break
10:45 Symposium 5: “A-typical” Ion channels/currents
Organized by Pietro Mesirca (IGF, University of Montpellier, France)
Rajan Sah (Iowa City, USA): SWELL1/LRRC8a mediated nutrient sensing.
Arnaud Monteil (Montpellier, France): The sodium leak channel: NALCN.
Anna Moroni (Milan, Italy): Engineering synthetic tools for the inhibition of cell excitability.
Selected speaker: Mallory Ducrozet (Lyon, France): Role of Translocon in calcium exchanges in cell compartments and in cell death, during myocardial infarct
12:30 Meeting closure
14:00 Airport shuttle departure